Development of a Physiologically Based Pharmacokinetic Model for Tegoprazan: Application for the Prediction of Drug-Drug Interactions with CYP3A4 Perpetrators

Tegoprazan is a novel potassium-competitive acid blocker (P-CAB) developed by CJ Healthcare (Korea) for the treatment of gastroesophageal reflux disease and helicobacter pylori infections. Tegoprazan is mainly metabolized by cytochrome P450 (CYP) 3A4. Considering the therapeutic indications, tegopra...

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Main Authors: Lien Thi Ngo (Author), Jaeyeon Lee (Author), Hwi-yeol Yun (Author), Jung-woo Chae (Author)
Format: Book
Published: MDPI AG, 2023-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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