The Characteristics Variation of Hepatic Progenitors after TGF-β1-Induced Transition and EGF-Induced Reversion

• Main Authors: Ping Wang (Author), Min Cong (Author), Tianhui Liu (Author), Aiting Yang (Author), Guangyong Sun (Author), Dong Zhang (Author), Jian Huang (Author), Shujie Sun (Author), Jia Mao (Author), Hong Ma (Author), Jidong Jia (Author), Hong You (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Profibrogenesis cytokine, transforming growth factor- (TGF-) β1, induces hepatic progenitors experiencing epithelial to mesenchymal transition (EMT) to matrix synthesis cells, even tumor initiating cells. Our previous data found that epidermal growth factor (EGF) blocks and reverses TGF-β1-induced t...