Intravenous Arginine Administration Downregulates NLRP3 Inflammasome Activity and Attenuates Acute Kidney Injury in Mice with Polymicrobial Sepsis

Acute kidney injury (AKI) is a major complication of sepsis. Nucleotide-binding domain-like receptor protein 3 (NLRP3) inflammasomes are multiprotein complexes that mediate septic AKI. L-arginine (Arg) is a conditionally essential amino acid in catabolic conditions and a substrate for nitric oxide (...

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Main Authors: Sharon Angela Tanuseputero (Author), Ming-Tsan Lin (Author), Sung-Ling Yeh (Author), Chiu-Li Yeh (Author)
Format: Book
Published: Hindawi Limited, 2020-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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