Genotyping for HLA Risk Alleles to Prevent Drug Hypersensitivity Reactions: Impact Analysis

• Główni autorzy: Lisanne E. N. Manson (Autor), Wilbert B. van den Hout (Autor), Henk-Jan Guchelaar (Autor)
• Format: Książka
• Wydane: MDPI AG, 2021-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Human Leukocyte Antigen (HLA) variants can be a risk factor for developing potentially fatal drug hypersensitivity reactions. Our aim was to estimate the potential impact of genotyping for the HLA risk alleles incorporated in the Dutch Pharmacogenetics Working Group (DPWG) guidelines in The Netherla...