Genome-wide significance for a modifier of age at neurological onset in Huntington's Disease at 6q23-24: the HD MAPS study

• Main Authors: Gillis Tammy (Author), Mysore Jayalakshmi (Author), Djoussé Luc (Author), Xu Gang (Author), Prakash Ranjana (Author), Wheeler Vanessa C (Author), Lazzarini Alice (Author), Ashizawa Tetsuo (Author), Jones Randi (Author), Paulsen Jane S (Author), Frontali Marina (Author), Novelletto Andrea (Author), McCusker Elizabeth (Author), Trent Ronald JA (Author), Klimek Mary (Author), Suchowersky Oksana (Author), García Carmen (Author), Gómez-Tortosa Estrella (Author), Frati Luigi (Author), Squitieri Ferdinando (Author), Rosenblatt Adam (Author), Margolis Russell L (Author), Ross Christopher A (Author), Nance Martha (Author), Morrison Patrick J (Author), Durr Alexandra (Author), Warby Simon C (Author), Hayden Michael R (Author), Li Jian-Liang (Author), Hakky Michael (Author), Cupples L Adrienne (Author), Saint-Hilaire Marie H (Author), Cha Jang-Ho J (Author), Hersch Steven M (Author), Penney John B (Author), Harrison Madaline B (Author), Perlman Susan L (Author), Zanko Andrea (Author), Abramson Ruth K (Author), Lechich Anthony J (Author), Duckett Ayana (Author), Marder Karen (Author), Conneally P Michael (Author), Gusella James F (Author), MacDonald Marcy E (Author), Myers Richard H (Author)
• Format: Book
• Published: BMC, 2006-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Age at onset of Huntington's disease (HD) is correlated with the size of the abnormal CAG repeat expansion in the <it>HD </it>gene; however, several studies have indicated that other genetic factors also contribute t...