An AI‐assisted integrated, scalable, single‐cell phenomic‐transcriptomic platform to elucidate intratumor heterogeneity against immune response

• Main Authors: Christopher P. Tostado (Author), Lucas Xian Da Ong (Author), Joel Jia Wei Heng (Author), Carlo Miccolis (Author), Shumei Chia (Author), Justine Jia Wen Seow (Author), Yi‐Chin Toh (Author), Ramanuj DasGupta (Author)
• Format: Book
• Published: Wiley, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract We present a novel framework combining single‐cell phenotypic data with single‐cell transcriptomic analysis to identify factors underpinning heterogeneity in antitumor immune response. We developed a pairwise, tumor‐immune discretized interaction assay between natural killer (NK‐92MI) cells...