Nintedanib Alleviates Experimental Colitis by Inhibiting CEBPB/PCK1 and CEBPB/EFNA1 Pathways

• Main Authors: Hailong Li (Author), Jinhe Li (Author), Ting Xiao (Author), Yayue Hu (Author), Ying Yang (Author), Xiaoting Gu (Author), Ge Jin (Author), Hailong Cao (Author), Honggang Zhou (Author), Cheng Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The super-enhancer, a cluster of enhancers with strong transcriptional activity, has become one of the most interesting topics in recent years. This study aimed to investigate pathogenic super-enhancer-driven genes in IBD and screen therapeutic drugs based on the results. In this study, through the...