Genomic cis-acting Sequences Improve Expression and Establishment of a Nonviral Vector

• 主要な著者: Claudia Hagedorn (著者), Michael N Antoniou (著者), Hans J Lipps (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2013-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The vector pEPI was the first nonviral and episomally replicating vector. Its functional element is an expression unit linked to a chromosomal scaffold/matrix attached region (S/MAR). The vector replicates autonomously with low copy number in various cell lines, is mitotically stable in the absence...