GE11 peptide conjugated selenium nanoparticles for EGFR targeted oridonin delivery to achieve enhanced anticancer efficacy by inhibiting EGFR-mediated PI3K/AKT and Ras/Raf/MEK/ERK pathways

• Glavni autori: Jiang Pi (Autor), Jinhuan Jiang (Autor), Huaihong Cai (Autor), Fen Yang (Autor), Hua Jin (Autor), Peihui Yang (Autor), Jiye Cai (Autor), Zheng W. Chen (Autor)
• Format: Knjiga
• Izdano: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Selenium nanoparticles (Se NPs) have attracted increasing interest in recent decades because of their anticancer, immunoregulation, and drug carrier functions. In this study, GE11 peptide-conjugated Se NPs (GE11-Se NPs), a nanosystem targeting EGFR over-expressed cancer cells, were synthesized for o...