Functionalized 3-hydroxy-3-aminoquinoline-oxindole hybrids as promising dual-function anti-plasmodials

• Main Authors: Bharvi Sharma (Author), Jenny Legac (Author), Nosipho Cele (Author), Paul Awolade (Author), Philip J. Rosenthal (Author), Parvesh Singh (Author), Vipan Kumar (Author)
• Format: Book
• Published: Elsevier, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Malaria parasites continue to pose a concern. Drug resistance underlines the need for new structural cores that, when combined with existing antimalarial frameworks, can partially re-sensitize drug-resistant parasites to available antimalarial drugs, such as chloroquine (CQ). Herein, we used "c...