N-of-1-pathways MixEnrich: advancing precision medicine via single-subject analysis in discovering dynamic changes of transcriptomes

• Main Authors: Qike Li (Author), A. Grant Schissler (Author), Vincent Gardeux (Author), Ikbel Achour (Author), Colleen Kenost (Author), Joanne Berghout (Author), Haiquan Li (Author), Hao Helen Zhang (Author), Yves A. Lussier (Author)
• 格式: 圖書
• 出版: BMC, 2017-05-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Abstract Background Transcriptome analytic tools are commonly used across patient cohorts to develop drugs and predict clinical outcomes. However, as precision medicine pursues more accurate and individualized treatment decisions, these methods are not designed to address single-patient transcriptom...