Effect of semaglutide and empagliflozin on cognitive function and hippocampal phosphoproteomic in obese mice

• Main Authors: Xiaoyi Chen (Author), Shuchun Chen (Author), Zelin Li (Author), Ruiyi Zhu (Author), Zhuoya Jia (Author), Jiangli Ban (Author), Ruoxi Zhen (Author), Xing Chen (Author), Xiaoyu Pan (Author), Qingjuan Ren (Author), Lin Yue (Author), Shu Niu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Based on the 4D label-free phosphoproteomic technique, we examined the differences in cognitive function and hippocampal phosphorylated protein expression in high-fat diet-induced obese mice after the intervention of semaglutide and empagliflozin, as well as the effects of both on protein...