Developmental metformin exposure does not rescue physiological impairments derived from early exposure to altered maternal metabolic state in offspring mice

• Autores principales: Lídia Cantacorps (Autor), Jiajie Zhu (Autor), Selma Yagoub (Autor), Bethany M. Coull (Autor), Joanne Falck (Autor), Robert A. Chesters (Autor), Katrin Ritter (Autor), Miguel Serrano-Lope (Autor), Katharina Tscherepentschuk (Autor), Lea-Sophie Kasch (Autor), Maya Paterson (Autor), Paula Täger (Autor), David Baidoe-Ansah (Autor), Shuchita Pandey (Autor), Carla Igual-Gil (Autor), Annett Braune (Autor), Rachel N. Lippert (Autor)
• Formato: Libro
• Publicado: Elsevier, 2024-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Objective: The incidence of gestational diabetes mellitus (GDM) and metabolic disorders during pregnancy are increasing globally. This has resulted in increased use of therapeutic interventions such as metformin to aid in glycemic control during pregnancy. Even though metformin can cross the placent...