Exploring Structure-Activity Relationships of Niclosamide-Based Colistin Potentiators in Colistin-Resistant Gram-Negative Bacteria

Exploring Structure-Activity Relationships of Niclosamide-Based Colistin Potentiators in Colistin-Resistant Gram-Negative Bacteria

Colistin is primarily used as a last resort antibiotic against highly resistant Gram-negative bacteria (GNB). Rising rates of colistin resistance, however, may limit future use of this agent. The anthelmintic drug niclosamide has been shown to enhance colistin activity in combination therapy, but a...

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Main Authors: Liam Berry (Author), Quinn Neale (Author), Rajat Arora (Author), Danyel Ramirez (Author), Marc Brizuela (Author), Ronald Domalaon (Author), Gilbert Arthur (Author), Frank Schweizer (Author)
Format: Book
Published: MDPI AG, 2024-01-01T00:00:00Z.
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