Single- and multiple-dose tolerability, safety, pharmacokinetics, and pharmacodynamics of the dual endothelin receptor antagonist aprocitentan in healthy adult and elderly subjects

Patricia N Sidharta,1 Meggane Melchior,1 Martin K Kankam,2 Jasper Dingemanse1 1Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil CH-4123, Switzerland; 2Vince and Associates Clinical Research, Overland Park, KS 66211, USA Background: Aprocitentan is an orally active, dual en...

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Main Authors: Sidharta PN (Author), Melchior M (Author), Kankam MK (Author), Dingemanse J (Author)
Format: Book
Published: Dove Medical Press, 2019-03-01T00:00:00Z.
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Call Number: A1234.567
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