Revealing t-tubules in striated muscle with new optical super-resolution microscopy techniques

• Main Authors: Isuru D. Jayasinghe (Author), Alexander H. Clowsley (Author), Michelle Munro (Author), Yufeng Hou (Author), David J. Crossman (Author), Christian Soeller (Author)
• Format: Book
• Published: PAGEPress Publications, 2014-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The t-tubular system plays a central role in the synchronisation of calcium signalling and excitation-contraction coupling in most striated muscle cells. Light microscopy has been used for imaging t-tubules for well over 100 years and together with electron microscopy (EM), has revealed the three-di...