Human Mesenchymal Stem Cells Display Reduced Expression of CD105 after Culture in Serum-Free Medium

• Main Authors: Peter Mark (Author), Mandy Kleinsorge (Author), Ralf Gaebel (Author), Cornelia A. Lux (Author), Anita Toelk (Author), Erik Pittermann (Author), Robert David (Author), Gustav Steinhoff (Author), Nan Ma (Author)
• Format: Book
• Published: Hindawi Limited, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Human Mesenchymal Stem Cells (hMSCs) present a promising tool for regenerative medicine. However, ex vivo expansion is necessary to obtain sufficient cells for clinical therapy. Conventional growth media usually contain the critical component fetal bovine serum. For clinical use, chemically defined...