Transcriptome profiling reveals significant changes in the gastric muscularis externa with obesity that partially overlap those that occur with idiopathic gastroparesis

• Main Authors: B. Paul Herring (Author), Meng Chen (Author), Plamen Mihaylov (Author), April M. Hoggatt (Author), Anita Gupta (Author), Attila Nakeeb (Author), Jennifer N. Choi (Author), John M. Wo (Author)
• Format: Book
• Published: BMC, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Gastric emptying is impaired in patients with gastroparesis whereas it is either unchanged or accelerated in obese individuals. The goal of the current study was to identify changes in gene expression in the stomach muscularis that may be contributing to altered gastric motility...