Improving prediction of tacrolimus concentration using a combination of population pharmacokinetic modeling and machine learning in chinese renal transplant recipients

• প্রধান লেখক: Yu-Ping Wang (লেখক), Xiao-Ling Lu (লেখক), Kun Shao (লেখক), Hao-Qiang Shi (লেখক), Pei-Jun Zhou (লেখক), Bing Chen (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

AimsThe population pharmacokinetic (PPK) model-based machine learning (ML) approach offers a novel perspective on individual concentration prediction. This study aimed to establish a PPK-based ML model for predicting tacrolimus (TAC) concentrations in Chinese renal transplant recipients.MethodsConve...