Improving prediction of tacrolimus concentration using a combination of population pharmacokinetic modeling and machine learning in chinese renal transplant recipients

AimsThe population pharmacokinetic (PPK) model-based machine learning (ML) approach offers a novel perspective on individual concentration prediction. This study aimed to establish a PPK-based ML model for predicting tacrolimus (TAC) concentrations in Chinese renal transplant recipients.MethodsConve...

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Main Authors: Yu-Ping Wang (Author), Xiao-Ling Lu (Author), Kun Shao (Author), Hao-Qiang Shi (Author), Pei-Jun Zhou (Author), Bing Chen (Author)
Format: Book
Published: Frontiers Media S.A., 2024-05-01T00:00:00Z.
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