High quality copy number and genotype data from FFPE samples using Molecular Inversion Probe (MIP) microarrays

• Main Authors: Bondy Melissa (Author), Walther Axel (Author), Warren Robert (Author), Richardson Andrea L (Author), Wang Zhigang C (Author), Moorhead Martin (Author), Zhang Li (Author), Sapolsky Ronald (Author), Karlin-Neumann George (Author), Carlton Victoria EH (Author), Wang Yuker (Author), Sahin Aysegul (Author), Krahe Ralf (Author), Tuna Musaffe (Author), Thompson Patricia A (Author), Spellman Paul T (Author), Gray Joe W (Author), Mills Gordon B (Author), Faham Malek (Author)
• Format: Book
• Published: BMC, 2009-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>A major challenge facing DNA copy number (CN) studies of tumors is that most banked samples with extensive clinical follow-up information are Formalin-Fixed Paraffin Embedded (FFPE). DNA from FFPE samples generally underperforms or s...