High quality copy number and genotype data from FFPE samples using Molecular Inversion Probe (MIP) microarrays

• Glavni autori: Bondy Melissa (Autor), Walther Axel (Autor), Warren Robert (Autor), Richardson Andrea L (Autor), Wang Zhigang C (Autor), Moorhead Martin (Autor), Zhang Li (Autor), Sapolsky Ronald (Autor), Karlin-Neumann George (Autor), Carlton Victoria EH (Autor), Wang Yuker (Autor), Sahin Aysegul (Autor), Krahe Ralf (Autor), Tuna Musaffe (Autor), Thompson Patricia A (Autor), Spellman Paul T (Autor), Gray Joe W (Autor), Mills Gordon B (Autor), Faham Malek (Autor)
• Format: Knjiga
• Izdano: BMC, 2009-02-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>A major challenge facing DNA copy number (CN) studies of tumors is that most banked samples with extensive clinical follow-up information are Formalin-Fixed Paraffin Embedded (FFPE). DNA from FFPE samples generally underperforms or s...