A Mitochondria-Penetrating Peptide Exerts Potent Anti-Plasmodium Activity and Localizes at Parasites' Mitochondria

• Main Authors: Sangdao Somsri (Author), Mathirut Mungthin (Author), Natthaporn Klubthawee (Author), Poom Adisakwattana (Author), Warunee Hanpithakpong (Author), Ratchaneewan Aunpad (Author)
• Format: Book
• Published: MDPI AG, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mitochondria are considered a novel drug target as they play a key role in energy production and programmed cell death of eukaryotic cells. The mitochondria of malaria parasites differ from those of their vertebrate hosts, contributing to the drug selectivity and the development of antimalarial drug...