Development and validation of the quantification of GIZH-298, possessing in the rat blood plasma by HPLC-UF

He technique of quantitative determination of a new compound GIZH-298 in the rat blood plasma was developed and validated. Analysis was performed by HPLC-UV. The method was linear in the range of 100-5000 ng/ml. Recovery of GIZH-298 was 86,88 %. Limit of detection was 100 ng/ml.

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Bibliographic Details
Main Authors: O. G. Gribakina (Author), R. V. Shevchenko (Author), G. B. Kolyvanov (Author), A. A. Litvin (Author), P. O. Bochkov (Author), S. S. Boyko (Author), V. P. Zherdev (Author)
Format: Book
Published: LLC "Publisher OKI", 2019-02-01T00:00:00Z.
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042 |a dc 
100 1 0 |a O. G. Gribakina  |e author 
700 1 0 |a R. V. Shevchenko  |e author 
700 1 0 |a G. B. Kolyvanov  |e author 
700 1 0 |a A. A. Litvin  |e author 
700 1 0 |a P. O. Bochkov  |e author 
700 1 0 |a S. S. Boyko  |e author 
700 1 0 |a V. P. Zherdev  |e author 
245 0 0 |a Development and validation of the quantification of GIZH-298, possessing in the rat blood plasma by HPLC-UF 
260 |b LLC "Publisher OKI",   |c 2019-02-01T00:00:00Z. 
500 |a 2587-7836 
500 |a 2686-8830 
500 |a 10.24411/2587-7836-2019-10046 
520 |a He technique of quantitative determination of a new compound GIZH-298 in the rat blood plasma was developed and validated. Analysis was performed by HPLC-UV. The method was linear in the range of 100-5000 ng/ml. Recovery of GIZH-298 was 86,88 %. Limit of detection was 100 ng/ml. 
546 |a RU 
690 |a гиж-298 
690 |a количественное определение 
690 |a высокоэффективная жидкостная хроматография 
690 |a плазма крови 
690 |a gizh-298 
690 |a rat blood plasma 
690 |a hplc-uv 
690 |a quantification 
690 |a Pharmacy and materia medica 
690 |a RS1-441 
655 7 |a article  |2 local 
786 0 |n Фармакокинетика и Фармакодинамика, Vol 0, Iss 2, Pp 41-45 (2019) 
787 0 |n https://www.pharmacokinetica.ru/jour/article/view/93 
787 0 |n https://doaj.org/toc/2587-7836 
787 0 |n https://doaj.org/toc/2686-8830 
856 4 1 |u https://doaj.org/article/e44f9f3c64d84451b942d108275d0e5a  |z Connect to this object online.