Development and validation of the quantification of GIZH-298, possessing in the rat blood plasma by HPLC-UF
He technique of quantitative determination of a new compound GIZH-298 in the rat blood plasma was developed and validated. Analysis was performed by HPLC-UV. The method was linear in the range of 100-5000 ng/ml. Recovery of GIZH-298 was 86,88 %. Limit of detection was 100 ng/ml.
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Format: | Book |
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LLC "Publisher OKI",
2019-02-01T00:00:00Z.
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LEADER | 00000 am a22000003u 4500 | ||
---|---|---|---|
001 | doaj_e44f9f3c64d84451b942d108275d0e5a | ||
042 | |a dc | ||
100 | 1 | 0 | |a O. G. Gribakina |e author |
700 | 1 | 0 | |a R. V. Shevchenko |e author |
700 | 1 | 0 | |a G. B. Kolyvanov |e author |
700 | 1 | 0 | |a A. A. Litvin |e author |
700 | 1 | 0 | |a P. O. Bochkov |e author |
700 | 1 | 0 | |a S. S. Boyko |e author |
700 | 1 | 0 | |a V. P. Zherdev |e author |
245 | 0 | 0 | |a Development and validation of the quantification of GIZH-298, possessing in the rat blood plasma by HPLC-UF |
260 | |b LLC "Publisher OKI", |c 2019-02-01T00:00:00Z. | ||
500 | |a 2587-7836 | ||
500 | |a 2686-8830 | ||
500 | |a 10.24411/2587-7836-2019-10046 | ||
520 | |a He technique of quantitative determination of a new compound GIZH-298 in the rat blood plasma was developed and validated. Analysis was performed by HPLC-UV. The method was linear in the range of 100-5000 ng/ml. Recovery of GIZH-298 was 86,88 %. Limit of detection was 100 ng/ml. | ||
546 | |a RU | ||
690 | |a гиж-298 | ||
690 | |a количественное определение | ||
690 | |a высокоэффективная жидкостная хроматография | ||
690 | |a плазма крови | ||
690 | |a gizh-298 | ||
690 | |a rat blood plasma | ||
690 | |a hplc-uv | ||
690 | |a quantification | ||
690 | |a Pharmacy and materia medica | ||
690 | |a RS1-441 | ||
655 | 7 | |a article |2 local | |
786 | 0 | |n Фармакокинетика и Фармакодинамика, Vol 0, Iss 2, Pp 41-45 (2019) | |
787 | 0 | |n https://www.pharmacokinetica.ru/jour/article/view/93 | |
787 | 0 | |n https://doaj.org/toc/2587-7836 | |
787 | 0 | |n https://doaj.org/toc/2686-8830 | |
856 | 4 | 1 | |u https://doaj.org/article/e44f9f3c64d84451b942d108275d0e5a |z Connect to this object online. |