Xue-Jie-San restricts ferroptosis in Crohn's disease via inhibiting FGL1/NF-κB/STAT3 positive feedback loop

• Main Authors: Ying Gao (Author), Zhaozheng Zhang (Author), Jun Du (Author), Xiao Yang (Author), Xiaopeng Wang (Author), Ke Wen (Author), Xueliang Sun (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2023-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Crohn's disease (CD) is an incurable inflammatory bowel disease due to unclear etiology and pathogenesis. Accumulating evidences have shown the harmful role of ferroptosis in CD onset and development. Additionally, fibrinogen-like protein 1 (FGL1) has been verified to be a potential therapeutic...