Pharmacokinetics and pharmacodynamics of anti-tuberculosis drugs: An evaluation of in vitro, in vivo methodologies and human studies

• Principais autores: Jan-Willem C. Alffenaar (Autor), Jurriaan E. M. de Steenwinkel (Autor), Andreas H. Diacon (Autor), Ulrika S. H. Simonsson (Autor), Shashikant Srivastava (Autor), Sebastian G. Wicha (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2022-12-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

There has been an increased interest in pharmacokinetics and pharmacodynamics (PKPD) of anti-tuberculosis drugs. A better understanding of the relationship between drug exposure, antimicrobial kill and acquired drug resistance is essential not only to optimize current treatment regimens but also to...