Immunogenicity of an adjuvanted broadly active influenza vaccine in immunocompromised and diverse populations

• Main Authors: Dylan A. Hendy (Author), Erik S. Pena (Author), Luis Ontiveros‐Padilla (Author), Timothy A. Dixon (Author), Denzel D. Middleton (Author), Grace L. Williamson (Author), Nicole Rose Lukesh (Author), Sean R. Simpson (Author), Rebeca T. Stiepel (Author), Md Jahirul Islam (Author), Michael A. Carlock (Author), Ted M. Ross (Author), Eric M. Bachelder (Author), Kristy M. Ainslie (Author)
• Format: Book
• Published: Wiley, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Influenza virus outbreaks are a major burden worldwide each year. Current vaccination strategies are inadequate due to antigenic drift/shift of the virus and the elicitation of low immune responses. The use of computationally optimized broadly reactive antigen (COBRA) hemagglutinin (HA) imm...