Vitexin attenuates chronic kidney disease by inhibiting renal tubular epithelial cell ferroptosis via NRF2 activation

• Main Authors: Jiayu Song (Author), Hongri Wang (Author), Jingyi Sheng (Author), Wen Zhang (Author), Juan Lei (Author), Weihua Gan (Author), Fangfang Cai (Author), Yunwen Yang (Author)
• Format: Book
• Published: BMC, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Chronic kidney disease (CKD) involves a variety of pathological processes, and ferroptosis plays a vital role in CKD progression. Targeting ferroptosis is a promising strategy for the treatment of CKD. However, inhibitors of ferroptosis have not been used in the clinical treatmen...