Catalase Overexpression Drives an Aggressive Phenotype in Glioblastoma

• Main Authors: Susanne Flor (Author), Claudia R. Oliva (Author), Md Yousuf Ali (Author), Kristen L. Coleman (Author), Jeremy D. Greenlee (Author), Karra A. Jones (Author), Varun Monga (Author), Corinne E. Griguer (Author)
• Format: Book
• Published: MDPI AG, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glioblastoma remains the deadliest form of brain cancer, largely because these tumors become resistant to standard of care treatment with radiation and chemotherapy. Intracellular production of reactive oxygen species (ROS) is necessary for chemo- and radiotherapy-induced cytotoxicity. Here, we asse...