Synthesis and Chemopreventive Potential of 5-FU/Genistein Hybrids on Colorectal Cancer Cells

• Main Authors: Gustavo Moreno-Quintero (Author), Wilson Castrillón-Lopez (Author), Angie Herrera-Ramirez (Author), Andrés F. Yepes-Pérez (Author), Jorge Quintero-Saumeth (Author), Wilson Cardona-Galeano (Author)
• Format: Book
• Published: MDPI AG, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A series of 5-FU-Genistein hybrids were synthesized and their structures were elucidated by spectroscopic analysis. The chemopreventive potential of these compounds was evaluated in human colon adenocarcinoma cells (SW480 and SW620) and non-malignant cell lines (HaCaT and CHO-K1). Hybrid <b>4a...