Synthesis and Chemopreventive Potential of 5-FU/Genistein Hybrids on Colorectal Cancer Cells

• Главные авторы: Gustavo Moreno-Quintero (Автор), Wilson Castrillón-Lopez (Автор), Angie Herrera-Ramirez (Автор), Andrés F. Yepes-Pérez (Автор), Jorge Quintero-Saumeth (Автор), Wilson Cardona-Galeano (Автор)
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• Опубликовано: MDPI AG, 2022-10-01T00:00:00Z.
• Предметы: article
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A series of 5-FU-Genistein hybrids were synthesized and their structures were elucidated by spectroscopic analysis. The chemopreventive potential of these compounds was evaluated in human colon adenocarcinoma cells (SW480 and SW620) and non-malignant cell lines (HaCaT and CHO-K1). Hybrid <b>4a...