Proteomic reference map for sarcopenia research: mass spectrometric identification of key muscle proteins located in the sarcomere, cytoskeleton and the extracellular matrix

• Main Authors: Paul Dowling (Author), Stephen Gargan (Author), Margit Zweyer (Author), Michael Henry (Author), Paula Meleady (Author), Dieter Swandulla (Author), Kay Ohlendieck (Author)
• Format: Book
• Published: PAGEPress Publications, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sarcopenia of old age is characterized by the progressive loss of skeletal muscle mass and concomitant decrease in contractile strength. Age-related skeletal muscle dysfunctions play a key pathophysiological role in the frailty syndrome and can result in a drastically diminished quality of life in t...