Quercetin 3, 3', 4', 5, 7-O- pentasulfate (QPS): A novel activator of protein disulfide isomerase
Aims: Design and synthesis of a novel 3, 3', 4', 5, 7-O- pentasulfated Quercetin (QPS) as an activator of protein disulfide isomerase (PDI). Main Methods: Based on an in silico analysis we show that QPS binds to a and b domain of PDI (−7.4 kcal/mol) unlike PDI inhibitor quercetin 3-rutinos...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2020-06-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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