Evaluation of Epidermal Growth Factor Receptor Gene Mutations in an Iranian Population with Non-Small Cell Lung Carcinoma

• Main Authors: Hamzeh Salmani (Author), Mahin Yahyaei (Author), Reza Raoofian (Author), Shiva Irani (Author), Iman Salahshouri Far (Author), Seyed Mohammad Akrami (Author)
• Format: Book
• Published: Tehran University of Medical Sciences, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Mutations of the epidermal growth factor receptor (EGFR) gene, predominantly in exons 18-21, have been highlighted to function as the crucial predictors of the response rate of patients with non-small cell lung cancer (NSCLC) to EGFR tyrosine kinase inhibitors (TKIs). Methods: This study...