Hesperidin Mitigates Cyclophosphamide-Induced Testicular Dysfunction via Altering the Hypothalamic Pituitary Gonadal Axis and Testicular Steroidogenesis, Inflammation, and Apoptosis in Male Rats

• Main Authors: Tarek Khamis (Author), Abdelmonem Awad Hegazy (Author), Samaa Salah Abd El-Fatah (Author), Eman Ramadan Abdelfattah (Author), Marwa Mohamed Mahmoud Abdelfattah (Author), Liana Mihaela Fericean (Author), Ahmed Hamed Arisha (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cyclophosphamide (CP) is a cytotoxic, cell cycle, non-specific, and antiproliferative drug. This study aimed to address the toxic effects of CP on male fertility and the possible ameliorative role of hesperidin (HSP). Thirty-two adult albino rats were randomly divided into four groups, namely, the n...