Single-cell RNA sequencing reveals the effects of high-fat diet on oocyte and early embryo development in female mice

• Main Authors: Qi Zhu (Author), Feng Li (Author), Hao Wang (Author), Xia Wang (Author), Yu Xiang (Author), Huimin Ding (Author), Honghui Wu (Author), Cen Xu (Author), Linglin Weng (Author), Jieyu Cai (Author), Tianyue Xu (Author), Na Liang (Author), Xiaoqi Hong (Author), Mingrui Xue (Author), Hongshan Ge (Author)
• Format: Book
• Published: BMC, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Obesity is a global health issue with detrimental effects on various human organs, including the reproductive system. Observational human data and several lines of animal experimental data suggest that maternal obesity impairs ovarian function and early embryo development, but th...