Glycyrrhizin, an inhibitor of HMGB1 induces autolysosomal degradation function and inhibits Helicobacter pylori infection

• Main Authors: Uzma Khan (Author), Bipul Chandra Karmakar (Author), Priyanka Basak (Author), Sangita Paul (Author), Animesh Gope (Author), Deotima Sarkar (Author), Asish Kumar Mukhopadhyay (Author), Shanta Dutta (Author), Sushmita Bhattacharya (Author)
• Format: Book
• Published: BMC, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Helicobacter pylori is a key agent for causing gastric complications linked with gastric disorders. In response to infection, host cells stimulate autophagy to maintain cellular homeostasis. However, H. pylori have evolved the ability to usurp the host's autophagic machinery...