Shen-Yuan-Dan Capsule Attenuates Atherosclerosis and Foam Cell Formation by Enhancing Autophagy and Inhibiting the PI3K/Akt/mTORC1 Signaling Pathway

• Autori principali: Mingxue Zhou (Autore), Pan Ren (Autore), Ying Zhang (Autore), Sinai Li (Autore), Mengjie Li (Autore), Ping Li (Autore), Juju Shang (Autore), Weihong Liu (Autore), Hongxu Liu (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2019-05-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Background and Aim: The phosphoinositide 3-kinase (PI3K)/Akt/mammalian target of rapamycin complex 1 (mTORC1) signaling pathway plays a crucial role in autophagy and inflammation. Our previous studies demonstrated that Shen-Yuan-Dan Capsule (SYDC), a Chinese medicine used for treating angina pectori...