Intratracheally Administered Peptide-Modified Lipid Admixture Containing Fasudil and/or DETA NONOate Ameliorates Various Pathologies of Pulmonary Arterial Hypertension

This study examined the therapeutic potential of a combination therapy using fasudil, a Rho-kinase inhibitor, and DETA NONOate (DN), a nitric oxide donor, delivered as a lipid admixture modified with a cyclic homing peptide known as CAR (CAR-lipid mixture) for the treatment of pulmonary arterial hyp...

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Main Authors: Tanoy Sarkar (Author), Sakib M. Moinuddin (Author), Ayman Isbatan (Author), Jiwang Chen (Author), David Mann (Author), Fakhrul Ahsan (Author)
Format: Book
Published: MDPI AG, 2023-11-01T00:00:00Z.
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