Cellular and molecular alterations in neurons and glial cells in inherited retinal degeneration

• Main Authors: Natalia Martínez-Gil (Author), Victoria Maneu (Author), Oksana Kutsyr (Author), Laura Fernández-Sánchez (Author), Xavier Sánchez-Sáez (Author), Carla Sánchez-Castillo (Author), Laura Campello (Author), Pedro Lax (Author), Isabel Pinilla (Author), Nicolás Cuenca (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Multiple gene mutations have been associated with inherited retinal dystrophies (IRDs). Despite the spectrum of phenotypes caused by the distinct mutations, IRDs display common physiopathology features. Cell death is accompanied by inflammation and oxidative stress. The vertebrate retina has several...