Assessment of Inhibitors of Pathogenic Crimean-Congo Hemorrhagic Fever Virus Strains Using Virus-Like Particles.

• Main Authors: Marko Zivcec (Author), Maureen G Metcalfe (Author), César G Albariño (Author), Lisa W Guerrero (Author), Scott D Pegan (Author), Christina F Spiropoulou (Author), Éric Bergeron (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Crimean-Congo hemorrhagic fever (CCHF) is an often lethal, acute inflammatory illness that affects a large geographic area. The disease is caused by infection with CCHF virus (CCHFV), a nairovirus from the Bunyaviridae family. Basic research on CCHFV has been severely hampered by biosafety requireme...