Complexity in the genetic architecture of leukoaraiosis in hypertensive sibships from the GENOA Study

• Main Authors: Jack Clifford R (Author), Mosley Thomas H (Author), Kelly Reagan J (Author), Fornage Myriam (Author), Sun Yan V (Author), Turner Stephen T (Author), Smith Jennifer A (Author), Kullo Iftikhar J (Author), Kardia Sharon LR (Author)
• Format: Book
• Published: BMC, 2009-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Subcortical white matter hyperintensity on magnetic resonance imaging (MRI) of the brain, referred to as leukoaraiosis, is associated with increased risk of stroke and dementia. Hypertension may contribute to leukoaraiosis by acceler...