Non-alcoholic fatty liver disease combined with rheumatoid arthritis exacerbates liver fibrosis by stimulating co-localization of PTRF and TLR4 in rats

• Ngā kaituhi matua: Shengpeng Zhang (Author), Peng Zhu (Author), Jianan Yuan (Author), Kunming Cheng (Author), Qixiang Xu (Author), Wei Chen (Author), Zui Pan (Author), Yongqiu Zheng (Author)
• Hōputu: Pukapuka
• I whakaputaina: Frontiers Media S.A., 2023-06-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Rheumatoid arthritis (RA) has a high prevalence in patients with non-alcoholic fatty liver disease (NAFLD); however, the underlying mechanism is unclear. To address this, our study established a rat model with both NAFLD and RA by feeding a high-fat diet (HFD) and administering intradermal injection...