Evaluation of the antitumor activity of 2-[3-(2-chloroethyl)-3-nitrosoureido]-1,3-propanediol (chlonisol) in C57BL/6 mice with intracranially transplanted B16 melanoma

• Main Authors: I. G. Murazov (Author), A. N. Stukov (Author), Iu. G. Zmitrichenko (Author), A. O. Niuganen (Author), G. V. Tochilnikov (Author), D. Ch. Latipova (Author), L. V. Filatova (Author), T. Yu. Semiglazova (Author)
• Format: Book
• Published: LLC "Publisher OKI", 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. The arsenal of antitumor drug therapy for melanoma brain metastases is limited. The search and study of new agents capable to penetrate the blood-brain barrier and provide a therapeutic effect against intracranial tumors remains an unmet clinical need. The aim is to evaluate the antitumo...