Evaluation of the antitumor activity of 2-[3-(2-chloroethyl)-3-nitrosoureido]-1,3-propanediol (chlonisol) in C57BL/6 mice with intracranially transplanted B16 melanoma

• Главные авторы: I. G. Murazov (Автор), A. N. Stukov (Автор), Iu. G. Zmitrichenko (Автор), A. O. Niuganen (Автор), G. V. Tochilnikov (Автор), D. Ch. Latipova (Автор), L. V. Filatova (Автор), T. Yu. Semiglazova (Автор)
• Формат: ‌
• Опубликовано: LLC "Publisher OKI", 2021-09-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Background. The arsenal of antitumor drug therapy for melanoma brain metastases is limited. The search and study of new agents capable to penetrate the blood-brain barrier and provide a therapeutic effect against intracranial tumors remains an unmet clinical need. The aim is to evaluate the antitumo...