DEVELOPMENT OF MURINE STEM CELLS WITH CONDITIONAL KNOCKOUT OF HUMANIZED SNCA GENE

• Main Authors: E. A. Patrakhanov (Author), V. M. Pokrovsky (Author), A. Yu. Karagodina (Author), A. M. Krayushkina (Author), N. S. Zhunusov (Author), A. V. Deykin (Author), M. V. Korokin (Author), M. V. Pokrovsky (Author), O. B. Altukhova (Author)
• Format: Book
• Published: Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

α-synuclein is one of the key molecular links in the pathogenesis of Parkinson's disease. The accumulated data indicate that pathogenic mutations in the Snca gene are associated with the development of neurodegenerative brain damage, indicating the relevance of studying the synuclein neurobiolo...