Comparison of PLA-Based Micelles and Microspheres as Carriers of Epothilone B and Rapamycin. The Effect of Delivery System and Polymer Composition on Drug Release and Cytotoxicity against MDA-MB-231 Breast Cancer Cells

• Váldodahkkit: Katarzyna Jelonek (Dahkki), Alicja Zajdel (Dahkki), Adam Wilczok (Dahkki), Bożena Kaczmarczyk (Dahkki), Monika Musiał-Kulik (Dahkki), Anna Hercog (Dahkki), Aleksander Foryś (Dahkki), Małgorzata Pastusiak (Dahkki), Janusz Kasperczyk (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2021-11-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Co-delivery of epothilone B (EpoB) and rapamycin (Rap) increases cytotoxicity against various kinds of cancers. However, the current challenge is to develop a drug delivery system (DDS) for the simultaneous delivery and release of these two drugs. Additionally, it is important to understand the rele...