Syndecan-1, an indicator of endothelial glycocalyx degradation, predicts outcome of patients admitted to an ICU with COVID-19

• Main Authors: Dong Zhang (Author), Liubing Li (Author), Yu Chen (Author), Jie Ma (Author), Yanli Yang (Author), Surita Aodeng (Author), Qiuju Cui (Author), Kedi Wen (Author), Meng Xiao (Author), Jing Xie (Author), Yingchun Xu (Author), Yongzhe Li (Author)
• Format: Book
• Published: BMC, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background We investigated the feasibility of two biomarkers of endothelial damage (Syndecan-1 and thrombomodulin) in coronavirus disease 2019 (COVID-19), and their association with inflammation, coagulopathy, and mortality. Methods The records of 49 COVID-19 patients who were admitted to a...