The Antiviral RNAi Response in Vector and Non-vector Cells against Orthobunyaviruses.

• Main Authors: Isabelle Dietrich (Author), Xiaohong Shi (Author), Melanie McFarlane (Author), Mick Watson (Author), Anne-Lie Blomström (Author), Jessica K Skelton (Author), Alain Kohl (Author), Richard M Elliott (Author), Esther Schnettler (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Vector arthropods control arbovirus replication and spread through antiviral innate immune responses including RNA interference (RNAi) pathways. Arbovirus infections have been shown to induce the exogenous small interfering RNA (siRNA) and Piwi-interacting RNA (piRNA) pathways, but direct...