Inhibitors of ubiquitin E3 ligase as potential new antimalarial drug leads

• Κύριοι συγγραφείς: Jagrati Jain (Συγγραφέας), Surendra K. Jain (Συγγραφέας), Larry A. Walker (Συγγραφέας), Babu L. Tekwani (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: BMC, 2017-06-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Abstract Background Protein ubiquitylation is an important post-translational regulation, which has been shown to be necessary for life cycle progression and survival of Plasmodium falciparum. Ubiquitin is a highly conserved 76 amino acid polypeptide, which attaches covalently to target proteins thr...