Understanding the Mechanisms and Treatment of Heart Failure: Quantitative Systems Pharmacology Models with a Focus on SGLT2 Inhibitors and Sex-Specific Differences

• Auteurs principaux: Jean François Ndiaye (Auteur), Fahima Nekka (Auteur), Morgan Craig (Auteur)
• Format: Livre
• Publié: MDPI AG, 2023-03-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Heart failure (HF), which is a major clinical and public health challenge, commonly develops when the myocardial muscle is unable to pump an adequate amount of blood at typical cardiac pressures to fulfill the body's metabolic needs, and compensatory mechanisms are compromised or fail to adjust...