Quercitrin neutralizes sPLA2IIa activity, reduces the inflammatory IL-6 level in PC3 cell lines, and exhibits anti-tumor activity in the EAC-bearing mice model

• Glavni autori: P. Sophiya (Autor), Deepadarshan Urs (Autor), Jafar K. Lone (Autor), A. S. Giresha (Autor), H. Krishna Ram (Autor), J. G. Manjunatha (Autor), Hamed A. El-Serehy (Autor), M. Narayanappa (Autor), J. Shankar (Autor), Ragini Bhardwaj (Autor), Sameer Ahmad Guru (Autor), K. K. Dharmappa (Autor)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Human phospholipase A2 group IIa (sPLA2IIa) is an inflammatory enzyme that plays a significant role in tumorigenesis. Inhibiting the sPLA2IIa enzyme with an effective molecule can reduce the inflammatory response and halt cancer progression. The present study evaluates quercitrin, a biflavonoid, for...