Development of controlled release dexketoprofen tablets and prediction of drug release using Artificial Neural Network (ANN) modelling

• Main Authors: Özlem Kışlal Saraçoğlu (Author), Mecit Orhan Uludağ (Author), Elif Derya Özdemir (Author), İsmail Tuncer Değim (Author)
• Format: Book
• Published: Universidade de São Paulo, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dexketoprofen trometamol (DT) is an active S (+) enantiomer of ketoprofen, and a non-steroidal anti-inflammatory agent. DT has a short biological half-life and the dosing interval is quite short when there is a need to maintain the desirable effect for longer time periods. Consequently, a controlled...