Angiotensin II Induces Oxidative Stress and Endothelial Dysfunction in Mouse Ophthalmic Arteries via Involvement of AT1 Receptors and NOX2

• Main Authors: Michael Birk (Author), Ewa Baum (Author), Jenia Kouchek Zadeh (Author), Caroline Manicam (Author), Norbert Pfeiffer (Author), Andreas Patzak (Author), Johanna Helmstädter (Author), Sebastian Steven (Author), Marin Kuntic (Author), Andreas Daiber (Author), Adrian Gericke (Author)
• Format: Book
• Published: MDPI AG, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Angiotensin II (Ang II) has been implicated in the pathophysiology of various age-dependent ocular diseases. The purpose of this study was to test the hypothesis that Ang II induces endothelial dysfunction in mouse ophthalmic arteries and to identify the underlying mechanisms. Ophthalmic arteries we...